Welcome to Real-World Wednesdays (RWW)

We are passionate about all things related to the collection, creation & use of Real-World Data (RWD) in generating Real-World Evidence (RWE) for clinical research, drug development, medical devices, value access and other activities for BioPharma and the Life Sciences!

Welcome to the site where you can see upcoming live Real-World Wednesdays (RWW) discussions as well as podcast recordings of past discussions. In addition, please join the club (form below) to receive occasional updates, calendar invites for upcoming live discussions, and to provide input into future activities of the club 🙂

Recent/Upcoming Live Discussions


Every Wednesday 11-12 U.S. Eastern Time we hold a live discussion on the Clubhouse App at the RWD & RWE Club. Please see upcoming discussions listed below.

27 May 2026

EP 217: Real-World Data Driving Better Healthcare Research

Listen to a conversation with Claire Manneh of Datavant on how health systems & researchers harness real-world data to strengthen research, partnerships, privacy protections & patient outcomes.

Listen to the Podcast

3 June 2026

EP 218: Medicine’s Next Chapter: Forces reshaping health & research

Mal Postings is back to explore TechnoHealth’s 12 Domains: AI-powered care, digital twins, agentic AI, quantum biology, and the move from reactive medicine to proactive health engineering.

Listen to the Podcast

10 June 2026

EP 219: From EHRs to Evidence: IRB Oversight in RWD Research

Returning guest Wendy Charles, PhD joins to discuss when IRB approval is required. Secondary EHR use, linked claims, and patient registries are driving RWE: When is IRB oversight not optional?

Join the conversation